Mgbakọ in vitro Fertilization

Usoro ọgwụgwọ fatịlaịza in vitro chọrọ ọtụtụ nhọpụta na ndị ọkachamara, ndị na-akwadebe di na nwunye maka usoro ahụ. Di na nwunye ahụ kwesịrị ka a kụziere ya gbasara usoro dị mgbagwoju anya dị kaogwu ogwu nke hormonal, ihe ize ndụ na mmetụta, yana oge nchere achọrọ. Ọgwụgwọ ndị ahụ dị oke ọnụ.

Na Quebec, kemgbe 2010, Régie de l'Assurance Maladie (RAMQ) eguzobela Mmemme Enyemaka Quebec nke na-enye ọrụ zuru oke nke na-ahụ maka enweghị ọmụmụ, gụnyere ọnụ ahịa nke okirikiri atọ kpaliri.⁹.

Na Frans, 4 in vitro fatịlaịza nnwale bụ nke mkpuchi ahụike kpuchie nke ọma.

1. Mkpali nke ovaries

Nzọụkwụ mbụ bụ inye nwanyị ahụ ọgwụgwọ hormone, na-abụkarị GnRH agonist.Gonadotropin na-ewepụta Hormone) iji zuru ike ovaries (lee akụkụ nke ọgwụ), dịka ọmụmaatụ Decapeptyl®, Suprefact®, Enantone® Synarel®, ma ọ bụ Lupron®.

Mgbe ahụ, ọgwụgwọ ahụ na-achọ ịbawanye ọnụ ọgụgụ follicles nke ndị na-emepụta ovary na ịchịkwa oge nke ovulation. Nwanyị ahụ kwesịrị ịnata injections nke gonadotropins na ọrụ FSH ma ọ bụ LH iji kpalie follicles tozuo ma kwe ka ha mepụta ọtụtụ oocytes. Ndị a bụ ọmụmaatụ Puregon®, Gonal F®, Fostimon® Metrodin-HP®, Bravelle®, Humegon® Ménopur® Merional® Repronex® Fertinex® Fertinorm®, Humegon® Ménopur® Merional® Repronex® Fertinex® Fertinorm®, Elonva®, Luvéris®…

Mgbe follicles toro nke ọma na ọkwa homonụ zuru oke, a na-ebute ovulation site na ntụtụ nke homonụ HCG.Gonadotropin chorionic mmadụ), dịka ọmụmaatụ HCG endo 1500®, HCG endo 5000® (Fr), Pregnyl®, Choriomon®, Profasi-HP®, Chorex®, Novarel®, Ovitrelle® Ovidrel® ®

A na-eme ultrasound pelvic na nyocha ọbara na usoro ọ bụla iji chọpụta uto follicle.

Enweghịzi follicles, enweghị akwa ọzọ…

Ovaries nwanyị na-emepụtakarị ma hapụ ya naanị otu akwa akwa kwa okirikiri. Ọ bụ ezie na nke a zuru ezu maka echiche nkịtị, maka ịga nke ọma in vitro fatịlaịza, ọ dị mma ka a ga-enweta akwa ndị tozuru oke. Ya mere ọ dị mkpa ịkwalite ọrụ ovarian onye ọrịa karịa ka ọ dị na mbụ. Ọgwụ ndị a na-enye n'oge ọgwụgwọ fatịlaịza in vitro na-akpata mmepe nke otutu ovarian follicles, si otú ahụ na-amụba ọnụ ọgụgụ nke àkwá ga-ekwe omume, si otú ahụ nwee ohere ịnweta embrayo a na-akụnye.

2. Nchịkọta oocytes tozuru okè

Mgbe awa 32 ruo 36 nke mkpali homonụ, a na-anakọta oocytes chara acha site na iji obere tube na agịga nke etinyere n'ime ikpu. A na-eme ihe enyemaka a n'okpuru mgbakasị mpaghara ma ọ bụ izugbe site na njikwa ultrasound n'ihi na ọ nwere ike na-egbu mgbu. A na-ahọrọ oocytes na ụlọ nyocha.

Le A na-anakọta semen awa ole na ole tupu mgbe ahụ (ma ọ bụ thawed n'otu ụbọchị), na spam na-ekewapụ na seminal ọmụmụ na-echekwara na 37 Celsius C.

3. Fatịlaịza

Awa ole na ole mgbe owuwe ihe ubi ha gasịrị, a na-etinye spermatozoa na oocytes na kọntaktị na mmiri omenala ruo ọtụtụ awa na okpomọkụ. spermatozoa motile na-abịa ozugbo, na-enweghị enyemaka mpụga, na kọntaktị na oocyte. Mana naanị otu spam ga-eme nke a. N'ozuzu, na nkezi, 50% nke oocytes ka a na-amụba.

Oocytes (ma ọ bụ zygotes) nke fatịlaịza na-amalite ịmụba. N'ime awa 24, zaịgọt na-aghọ embrayo nke mkpụrụ ndụ 2 ruo 4.

4. Mbufe embrayo

Ụbọchị abụọ ruo ise mgbe njikọta spam nwoke na akwa nwanyị gachara, a na-ebufe embrayo otu ma ọ bụ abụọ n'ime akpanwa nwanyị. Mbufe embrayo bụ usoro dị mfe na enweghị mgbu nke a na-eme site na kateta dị gịrịgịrị ma na-agbanwe agbanwe nke etinyere na ikpu n'ime akpanwa. A na-edobe ẹmbrayo n'ime akpanwa wee tolite ebe ahụ ruo mgbe etinyere ya.

Mgbe usoro a gasịrị, nwanyị ahụ nwere ike ịmaliteghachi ọrụ ya.

Enwere ike ịchekwa otu embrayo ma ọ bụ karịa (nke a na-akpọ supernumeraries) site na oyi kpọnwụrụ maka nyocha ọzọ.

Mgbe nke ahụ gasịrị, dọkịta nwere ike inye ọgwụgwọ ọgwụgwọ hormonal, yana n'ezie ndenye ọgwụ maka nyocha ime ime iji hụ ma IVF ọ dị irè.

Ọtụtụ usoro ọgwụgwọ na-adị mkpa mgbe ụfọdụ tupu ime ime nke ọma. Ma n'ụzọ dị mwute, ụfọdụ di na nwunye adịghị atụ ime n'agbanyeghị ọtụtụ mgbalị.

Ndụmọdụ tupu IVF: 

• Kwụsị ise siga (nwoke na nwanyị!), N'ihi na ọ na-ebelata ohere ịtụrụ ime.
• Mee mgbatị ahụ ma gbalịsie ike maka ịdị arọ dị mma. Ọ na-enyere aka inwe ezigbo ọmụmụ.
• Maka ụmụ nwanyị: were vitamin B9 tupu ịtụrụ ime, n'ihi na nke a na-ebelata ohere nke nkwarụ na nwa e bu n'afọ.
• Nweta ọgwụ mgbochi flu (ọ nwere ike ibute ime ọpụpụ).