Mmiri Alendronic

General ịka nká nke ahụ na menopause na-emekarị ka mbibi nke ahụ anụ ahụ ọkpụkpụ. Nsonaazụ usoro a dị oke njọ. Ọ bụ ya mere ị ga-eji tinye oge na mbọ dị ukwuu iji kwụsị mmepe nke ọrịa ndị dị otú ahụ.

Enwere ike inwe ọtụtụ ihe kpatara ọdịdị osteoprosis na ọtụtụ ọrịa anụ ahụ ndị ọzọ. Ndị a gụnyere ị smokingụ sịga, ibu mkpụrụ ndụ ihe nketa, nsogbu metabolic, yana ibi ndụ nke ịnọ otu ebe.

Maka ọgwụgwọ dị irè nke osteoporosis na ntọala nlekọta ahụike, alendronic acid na-abịakarị ịzọpụta. Ihe a na - egbochi ịka nká nke anụ ahụ ọkpụkpụ, ụcha ya, Ọzọkwa, alendronic acid adịghị adabere na homonụ, nke na - eme ka ọ dị mkpa n'ọgụ megide osteoporosis na ọtụtụ ọrịa ndị ọzọ.

N'ụzọ dị mwute, ọ dịghị ngwaahịa na okike nwere alendronic acid. Alendronic acid bụ ihe sịntetịt enwetara site n'aka arụrụ arụ.

Agbanyeghị, n'ime usoro ọgwụgwọ ọrịa ogbu na nkwonkwo maka mbibi ọkpụkpụ, ndị na-edozi ahụ na-ekwukarị usoro ihe oriri kwesịrị ekwesị nke na-enye gị ohere ijikọta oriri alendronic acid na nri nke na-eme ka ọgwụgwọ osteoporosis dị irè karị.

Nri nwere oke nri dị mkpa iji lụso mmebi ọkpụkpụ ọgụ:

Ekwesịrị ịkpachara anya site na ngwaahịa ndị dị ka kọfị, koko-cola na ihe ndị ọzọ nwere caffeinated na-egbochi nnabata calcium. Mayonezi, margarine na ịgbasa, mmanu abuba na abụba atụrụ na-egbochikwa nnabata calcium, na-emebi mmịnye ya n'ime eriri afọ. Mmanya na-aba n'anya, yana ise siga, na-eme otu ụzọ ahụ na ahụ.

Njirimara niile nke alendronic acid

Alendronic acid bụ ihe eji emepụta sịntetik nke ihe pyrophosphate. Acid bụ nke klas nke bisphosphotanes, aha zuru ezu bụ aminobiphosphonateỌ bụ ntụ ntụ na-acha ọcha nke na-agbaze nke ọma na mmiri.

N'otu oge n'ime ahụ, alendronic acid na-abanye ngwa ngwa n'ime anụ ahụ dị nro, mgbe nke ahụ gasịrị, ọ ruru ọkpụkpụ. A na-anyụpụ ya na mamịrị. N'ime ahụ mmadụ, alendronic acid anaghị agafe usoro nke metabolism. Alendronate agbakwunyere na anụ ahụ ọkpụkpụ, na-egbochi mbibi ya akaghi aka.

Ọ dị mmadụ mkpa kwa ụbọchị maka alendronic acid:

Maka mgbochi nke osteoporosis, ndị dọkịta na-atụ aro ị takingụ 5 mg nke ihe a kwa ụbọchị. Site na mmepe nke osteoporosis, a na-atụ aro ka ị were alendronic acid na 10 mg kwa ụbọchị. Ọ bụrụ na mmadụ na-arịa ọrịa Paget, a na-atụ aro ka ọ were 40 mg kwa ụbọchị maka ọnwa isii.

Iwu maka ị aleụ alendronic acid

A na-atụ aro ka a na-ewere Alendronic acid n'ụtụtụ na afo efu na iko mmiri. A naghị atụ aro ka ị jiri tupu ị lakpuo ụra. Maka otu ihe ahụ, ọ naghị atụ aro ka iwere ọnọdụ dị larịị ozugbo ewerechara ihe ahụ maka nkeji iri atọ. Iwu a dị mfe ga - enyere gị aka izere mmepe nke esophagitis (mbufụt nke mkpuchi nke esophagus).

Mkpa maka alendronic acid na-abawanye:

• na ọrịa ọkpụkpụ;
• ya na okpukpu okpukpu karia;
• ya na hypercalcemia;
• na nsọpu;
• ya na ọrịa Paget.

Mkpa maka alendronic acid belatara:

• na-enwewanye uche na ihe ahụ;
• n'oge ime ime;
• n'oge lactation;
• na nwata;
• na afọ mgbu;
• ya na afo na duodenal ọnya;
• ya na achalasia nke akpiri;
• gbasara akụrụ odida;
• na dysphagia;
• enweghi vitamin D;
• ya na hypocalcemia.

Ọụ nke alendronic acid

Maka mgbakwunye nke alendronic acid zuru oke, a na -atụ aro ka ị drinkụ mmanya awa abụọ tupu nri. Achọpụtala ihe ahụ ka ọ ghara ịmịkọrọ nke ọma mgbe ewere ya n'afọ zuru oke. Ma ọ bụrụ n'otu oge ị na -a coffeeụ kọfị ma ọ bụ tii, soda, ma ọ bụ ihe ọ orangeụ orangeụ oroma, mgbe ahụ pasent ahụ ga -agbada ọbụna karịa. Mana ranitidine ga -amụba nnabata ahụ okpukpu abụọ.

Ihe ndị na-emetụta ọdịnaya nke alendronic acid na ahụ

Dịka e kwuworo, alendronic acid bụ ihe sịntetik, nke pụtara na ihe mbụ bụ ịmụrụ ọgwụ na ịmachi ọgwụ dịka ntuziaka dọkịta.

Nke abuo, ọ na-emetụta mmetụ nke acid n'ime ahụ nke ọma na otu esi eji alendronic acid eme ihe. Acid dị mma nke ọma tupu nri - na afọ zuru ezu, alendronic acid agaghị etinye obi gị dum ma ọlị.

Nke ato, ọmụmụ egosila na iji ogologo oge, ị ,ụ ọgwụ ọjọọ emee na ahụ na-akwụsị ịzaghachi alendronic acid.

Nke anọ, ojiji nke alendronic acid, yana ihe ndị na-ekwekọghị na ya, na-ebelata nsị ya nke ukwuu.