Ihe ịrịba ama ụlọ ọgwụ nke cholestasis bụ nke a jaundice (acha odo odo nke akpụkpọ ahụ na ihe ndị dị mkpa) jikọtara ya urine urine, stool agba na otu ichichi (itching).

N'ihe banyere cholestasis extrahepatic, hepatomegaly (mmụba nke imeju achọpụtara na palpation nke afọ), dọkịta nwere ike ịhụ nnukwu ọnya afọ na ahụ ọkụ n'oge nyocha ahụ.

Dabere na ihe kpatara cholestasis, enwere ike ịchọta ihe ịrịba ama ụlọ ọgwụ ndị ọzọ na-abụghị nke akọwapụtara (dịka ịbelata ibu na kansa).

Nnwale ụlọ nyocha nke ọbara na -egosi:

-a mụbara alkaline phosphatase nke bụ isi ihe na -achọpụta cholestasis.

-bawanye na gamma-glutamyl transpeptidase (gGT). Mmụba a abụghị nke akọwapụtara maka cholestasis ma enwere ike ịhụ ya na nsogbu imeju na biliary niile (dịka ọmụmaatụ mmanya)

-mmụba nke bilirubin jikọtara ọnụ, nke na -ahụ maka jaundice

-ihe ịrịba ama nke ụkọ vitamin A, D, E, K

-mbelata ọkwa prothrombin (PT) jikọtara na mbelata ihe V (protein coagulation) na ezughi oke hepatocellular.

Iji chọpụta ihe kpatara cholestasis,Abdominal ultrasound bụ nyocha nke ahịrị nke mbụ, na-egosi mmụba nke ọwa mmiri bile n'ihe gbasara cholestasis extrahepatic. N'ihe banyere cholestasis intrahepatic, ultrasound afọ anaghị ahụ mgbasa nke bile ducts.

Dị ka ebumnuche nke abụọ, dọkịta nwere ike ịhọpụta nyocha redio ọzọ:

-cholangiopancreatography (x-ray nke bile ducts mgbe ejiri ngwaahịa dị iche)

- ihe nyocha afọ

-Ihe MRI (Nchọpụta Resonance Magnetic Nuclear) nke ọwa mmiri bile

-nyocha nke endoscopy

Ọ bụrụ na enweghị mmekpa ahụ nke ọwa mmiri bile gosipụtara site na ultrasound, a na -eme nyocha ndị ọzọ iji gosipụta ihe kpatara cholestasis:

-nwale ọbara pụrụ iche (ịchọ ọgwụ mgbochi mitochondrial na ọgwụ mgbochi antinuclear) nwere ike bụrụ ihe na-egosi isi ọrịa biliary cirrhosis.

- enwere ike ime nchọta maka nje na -ahụ maka ịba ọcha n'anya

Ọ bụrụ na nyocha ndị a dị iche iche ekpughepụtaghị otu ihe kpatara ya, ọ ga -adị mkpa ka ị mee biopsy imeju.