Hormone na-akpali akpali nke follicle, ma ọ bụ FSH, bụ isi homonụ nke ọmụmụ n'ime ma nwoke ma nwanyị. Nke a bụ ya mere n'oge nlele ọmụmụ, a na-enyocha ọnụego ya nke ọma.

N'ime ụmụ nwanyị

HSF na-apụta na akụkụ mbụ nke okirikiri ovarian, nke a maara dị ka akụkụ follicular. N'ime oge a, nke na-amalite n'ụbọchị mbụ nke nsọ nsọ ma kwụsị n'oge ovulation, hypothalamus na-ezobe neurohormone, GnRH (hormone na-ahapụ gonadotropin). Mmeghachi omume yinye ga-esochi:

• GnRH na-akpali pituitary gland, nke na nzaghachi na-ezo FSH;
• n'okpuru mmetụta nke FSH, ihe dị ka iri abụọ ovarian follicles ga-amalite itolite;
• ndị a na-eto eto follicles ga-n'aka secrete estrogen, na-ahụ maka ndim nke uterine lining iji kwadebe akpanwa iji na-ekwe omume fatịlaịza akwa;
• N'ime otu ahụ, otu follicle, nke a na-akpọ follicle kachasị, na-enweta ovulation. A ga-ekpochapụ ndị ọzọ;
• mgbe a na-ahọrọ follicle preovulatory kachasị, mmepụta estrogen na-abawanye nke ọma. Mmụba a na-ebute mmụba na LH (hormone luteinizing) nke ga-akpalite ovulation: follicle tozuru oke na-agbawa wee hapụ oocyte.

N'etiti mmeghachi omume agbụ a, FSH bụ isi homonụ maka ọmụmụ.

N'ime mmadụ

FSH na-etinye aka na spermatogenesis na nzuzo nke testosterone. Ọ na-akpali sel Sertoli nke na-emepụta spam na testes.

N'ime ụmụ nwanyị, Enwere ike ịnye ọgwụ FSH n'ọnọdụ dị iche iche:

• na ihe omume nke amenorrhea bụ isi na / ma ọ bụ mbubreyo: a na-eme usoro ọgwụgwọ FSH na LH iji chọpụta ọdịiche dị n'etiti isi (ụdị ovarian) ma ọ bụ nke abụọ (isi mmalite: hypothalamus ma ọ bụ pituitary) hypogonadism;
• n'ihe banyere amenorrhea nke abụọ;
• N'ọnọdụ nsogbu ọmụmụ, a na-eme nyocha nke hormonal site na usoro nke homonụ mmekọahụ dị iche iche: follicle stimulating hormone (FSH), estradiol, luteinizing hormone (LH), hormone antimuleric (AMH) na ụfọdụ prolactin, TSH (thyroid gland). ), testosterone. Nnwale maka FSH na-enyere aka nyochaa ebe nchekwa nwa nwa na ogo ovulation. Ọ na-enye ohere ịmata ma ọ bụrụ na ọrịa ovulation ma ọ bụ amenorrhea bụ n'ihi na ovarian ịka nká ma ọ bụ na pituitary gland na-etinye aka.
• na menopause, mkpebi siri ike nke FSH agaghịzi akwado ịkwado mmalite nke tupu menopause na menopause (HAS, 2005) (1).

N'ime mmadụ

Enwere ike ime nyocha FSH dị ka akụkụ nke nyocha ọmụmụ, n'ihu spermogram abnormality (azoospermia ma ọ bụ oligospermia siri ike), iji chọpụta hypogonadism.

A na-ewere nha homonụ site na nyocha ọbara, ọ bụghị na afọ efu.

• N'ime ụmụ nwanyị, a na-eme mkpebi nke FSH, LH na estradiol na 2nd, 3rd ma ọ bụ 4th ụbọchị nke okirikiri na ụlọ nyocha nyocha.
• N'ime mmadụ, enwere ike ịme usoro onunu ogwu FSH n'oge ọ bụla.

N'ime ụmụ nwanyị:

• mmụba pụtara ìhè na FSH na LH na-egosi ọdịda ovarian bụ isi;
• Mbelata dị ukwuu na LH na FSH na-egosipụtakarị mmebi nke gland pituitary, nke mbụ ma ọ bụ nke abụọ ( tumor, pituitary necrosis, hypophysectomy, wdg);
• Ọ bụrụ na FSH dị elu na / ma ọ bụ estradiol dị ala, a na-enyo enyo mbelata nke nchekwa ovarian ("oge menopause").

N'ime mmadụ:

• ọkwa FSH dị elu na-egosi mmebi tubular testicular ma ọ bụ seminiferous;
• Ọ bụrụ na ọ dị ala, a na-enyo enyo itinye aka na "elu" (hypathalamus, pituitary). A ga-eme MRI na nyocha ọbara mgbakwunye iji chọpụta ụkọ pituitary.

N'ime ụmụ nwanyị:

• N'ọnọdụ ọdịda ovarian ma ọ bụ itinye aka na pituitary gland, a ga-enye ọgwụgwọ mkpali ovarian. Ebumnobi ya bụ mmepụta nke otu oocytes ma ọ bụ abụọ tozuru okè. Usoro dị iche iche dị, site n'ọnụ ọnụ ma ọ bụ injections;
• n'ọnọdụ nke menopause akaghi aka, enwere ike inye onyinye oocyte.

N'ime mmadụ:

• Ọ bụrụ na hypogonatotropic hypogonadism (mgbanwe nke hypotalamic-pituitary axis) na azoospermia siri ike ma ọ bụ oligospermia, a ga-enye ọgwụgwọ iji weghachi spermatogenesis. Enwere ike iji ụdị mkpụrụ ndụ abụọ: gonadotropins nwere ọrụ FSH na gonadotropins nwere ọrụ LH. Usoro, nke dịgasị iche dabere na onye ọrịa, na-adịru ọnwa 3 ruo 4, ma ọ bụ karịa n'ọnọdụ ụfọdụ.
• Ọ bụrụ na mgbanwe mgbanwe spam siri ike na ụfọdụ azoospermia (nke enwere ike ịwepụ spam na epididymis ma ọ bụ testis), enwere ike ịnye IVF na ICSI. Usoro AMP a gụnyere ịgbanye spam ozugbo n'ime cytoplasm nke oocyte tozuru okè;
• Enwere ike inye di na nwunye onyinye spam ma ọ bụrụ na enweghi ike iweghachi spermatogenesis.