Vasculitis nke arịa etiti

Peri Arteritis Nodosa ma ọ bụ PAN

Periarteritis nodosa (PAN) bụ angeitis necrotizing nke na-adịghị ahụkebe nke nwere ike imetụta ọtụtụ akụkụ ahụ, nke a na-amaghị nke ọma (ụdị ụfọdụ kwenyere na ha jikọtara ya na nje ịba ọcha n'anya B).

Ndị ọrịa na-enwekarị mmebi na ọnọdụ ha n'ozuzu ya na oke ibu, ahụ ọkụ, wdg.

Mgbu akwara dị na ọkara nke ikpe ahụ. Ha na-esiwanye ike, na-agbasa, na-apụta n'amaghị ama ma ọ bụ na-akpalite site na nrụgide, nke nwere ike kpọgide onye ọrịa n'àkwà n'ihi oke mgbu na imefusị ahụ ike ...

Mgbu nkwonkwo na-ebutekarị nnukwu nkwonkwo akụkụ: ikpere, nkwonkwo ụkwụ, ikiaka na nkwojiaka.

A na-ahụkarị mmebi nke irighiri akwara a na-akpọ multineuritis, na-emetụta ọtụtụ irighiri akwara dị ka sciatica, mpụga ma ọ bụ n'ime popliteal, radial, ulnar ma ọ bụ akwara etiti ma na-ejikọta ya na edema dịpụrụ adịpụ. Neuritis na-adịghị agwọ ọrịa na-emecha na-eduga na atrophy nke uru ahụ nke akwara ahụ metụtara.

Vasculitis nwekwara ike imetụta ụbụrụ ụbụrụ na-adịkarị obere, nke nwere ike ibute Akwụkwụ na-adọ, hemiplegia, ọrịa strok, ischemia ma ọ bụ ọbara ọgbụgba.

Ihe ịrịba ama na-egosi na ọkwa akpụkpọ ahụ bụ purpura (ntụpọ na-acha odo odo nke na-adịghị ada mgbe a na-agbanye ya) na-agbapụta ma na-abanye n'ime ya, karịsịa na akụkụ ụkwụ ala ma ọ bụ ndụ, na-emepụta ụdị meshes (livedo reticularis) ma ọ bụ mottles (livedo racemosa) na-acha ọcha na ụkwụ. Anyị nwekwara ike ịhụ ihe omume Raynaud (mkpịsị aka ole na ole na-acha ọcha na oyi), ma ọ bụ ọbụna mkpịsị aka ma ọ bụ mkpịsị ụkwụ gangrene.

Orchitis (mbufụt nke testicle) bụ otu n'ime ihe ngosi PAN na-ahụkarị, nke kpatara vasculitis nke akwara testicular nke nwere ike iduga necrosis testicular.

Ọrịa na-egbu egbu dị ndụ dị n'ọtụtụ ndị ọrịa nwere PAN (mmụba nke sedimentation ọnụego karịa 60 mm na elekere mbụ, na C Reactive Protein, wdg), nnukwu hyper eosinophilia (mmụba na eosinophilic polynuclear sel ọcha).

Ọrịa ịba ọcha n'anya B na-ebute ọnụnọ nke antigen HB n'ihe dịka ¼ ruo 1/3 nke ndị ọrịa

Angiography na-ekpughe microaneurysms na stenosis (mbelata na caliber ma ọ bụ tapering ọdịdị) nke ọkara caliber arịa.

Ọgwụgwọ PAN na-amalite site na ọgwụgwọ corticosteroid, mgbe ụfọdụ na-ejikọta ya na immunosuppressants (karịsịa cyclophosphamide)

Biotherapies na-ewere ọnọdụ na njikwa nke PAN, karịsịa rituximab (mgbochi CD20).

Ọrịa buerger

Ọrịa Buerger ma ọ bụ thromboangiitis obliterans bụ angiitis na-emetụta akụkụ nke obere akwara na ọkara na veins nke ala na elu aka, na-akpata thrombosis na recanalization nke arịa ndị metụtara. Ọrịa a na-ahụkarị n'Eshia na n'etiti ndị Juu Ashkenazi.

Ọ na-apụta na onye ọrịa na-eto eto (ihe na-erughị afọ 45), na-esekarị anwụrụ ọkụ, onye na-amalite igosipụta ngosipụta nke arteritis n'oge ndụ ya (ischemia nke mkpịsị aka ma ọ bụ mkpịsị ụkwụ, claudication intermittent, ọnya ischemic arterial ma ọ bụ gangrene nke ụkwụ, wdg).

Arteriography na-ekpughe mmebi nke akwara ndị dị anya.

Ọgwụgwọ na-agụnye ịkwụsị ise siga kpamkpam, nke na-ebute ọrịa na-akawanye njọ.

Dọkịta na-edepụta ọgwụ vasodilator na antiplatelet dịka aspirin

Enwere ike ịchọ ịwa ahụ revascularization.

Kawasaki's Maladie

Ọrịa Kawasaki ma ọ bụ "adeno-cutaneous-mucous syndrome" bụ ọrịa vasculitis nke na-emetụta ókèala nke akwara ọbara na-ahụ maka ọrịa akwara ọbara nke nwere ike ịbụ isi iyi nke ọnwụ, karịsịa na ụmụaka nọ n'agbata ọnwa isii na afọ ise nwere ọnụ ọgụgụ kasị elu. mgbe ọ dị afọ iri na asatọ.

Ọrịa na-ewere ọnọdụ n'ụzọ atọ n'ime ọtụtụ izu

Oge dị oke njọ (na-adịru ụbọchị 7 ruo ụbọchị 14): ahụ ọkụ na-acha ọkụ na ọdịdị nke "egbugbere ọnụ cherry", "ire strawberry", "anya na-agbanye" site na conjunctivitis bilateral, "nwa na-adịghị ahụkebe", edema na ọbara ọbara nke aka na ụkwụ. Dị ka o kwesịrị, ekwesịrị ịmalite ọgwụgwọ n'oge a iji belata ihe ize ndụ nke ọrịa obi

Usoro dị ala (ụbọchị 14 ruo 28) na-ebute peeling nke mkpịsị aka mkpịsị aka na mkpịsị ụkwụ na-amalite gburugburu ntu. Ọ bụ n'oge a ka aneurysms akwara na-etolite

Oge convalescent, nke na-abụkarị enweghị akara, mana n'ime oge nsogbu obi mberede nwere ike ime n'ihi nguzobe nke akwara akwara n'oge gara aga.

Ihe ịrịba ama ndị ọzọ bụ ọkụ ọkụ diaper, na-acha uhie uhie na-egbuke egbuke nke na-emerụ ahụ, ihe ịrịba ama obi (mgbe obi, ọrịa obi, ọrịa Electro CardioGram, pericarditis, myocarditis ...), digestive (afọ ọsịsa, vomiting, mgbu afọ ...), Neurological (aseptic meningitis, convulsions). , ahụ mkpọnwụ), mmamịrị (mmiri pus na mmamịrị, urethritis), ọrịa ogbu na nkwonkwo…

A na-egosipụta mmụba dị ịrịba ama n'ime ọbara site na ọnụ ọgụgụ sedimentation karịrị 100mm na elekere mbụ na protein C-reactive dị elu, mmụba pụtara ìhè na sel ọbara ọcha polynuclear karịa 20 ọcha / mm000, yana mmụba nke platelet.

Ọgwụgwọ na-adabere na immunoglobulins ịgbara intravenously (IV Ig) ozugbo enwere ike iji belata ihe ize ndụ nke anaurysm akwara obi. Ọ bụrụ na IVIG adịghị arụ ọrụ, ndị dọkịta na-eji cortisone intravenous ma ọ bụ aspirin.