La bilirubin bụ a ink ọ bụghị soluble na mmiri nke odo agba, n'ihi na mmebi nkehaemoglobin. Ọ bụ isi ihe agba agba nke ọbụna. A na-emepụta ya na sel nke anụ ahụ udu na ụmị ọkpụkpụ, wee na-ebuga ya site na ọbara site na albumin na imeju. Ozugbo ọ dị n'ime imeju, a na-ejikọta ya na gluconic acid ma na-agbaze na mmiri. N'ime eriri afọ, bilirubin conjugated na-enye stool agba aja aja.

Dọkịta ahụ ga-enye iwu ka a nyocha ọbara maka bilirubin ma ọ bụrụ na ọ na-enyo enyo, dịka ọmụmaatụ:

• ọrịa hepatobiliary: ọnọdụ na-emetụta ndị imeju (ịba ọcha n'anya bụ ihe a na-ahụkarị) na / ma ọ bụ bile ducts
• hemolytic syndromes (nke a na-akpọ mbibi na-adịghị mma nke mkpụrụ ndụ ọbara uhie)
• ma ọ bụ jaundice nke nwa amụrụ ọhụrụ, nke a na-akpọkwa jaundice nke nwa amụrụ ọhụrụ

Maka ule bilirubin, ekwesịrị ịme nyocha ọbara, nke nwere nyocha ọbara venous. A na-atụ aro ka ị ghara iri ma ọ bụ ṅụọ ihe ọ dịkarịa ala awa 4 tupu nyocha ọbara. Dọkịta ahụ nwekwara ike ịgwa onye ọrịa ka ọ kwụsị ịṅụ ọgwụ ụfọdụ nwere ike imetụta nsonaazụ ule bilirubin.

Ngụkọta bilirubin n'ọbara na-adịkarị n'etiti 0,3 na 1,9 mg / dl (milligram kwa deciliter). Ọnụ ọgụgụ nke bilirubin conjugated (nke a na-akpọkwa bilirubin kpọmkwem) na-adịkarị n'etiti 0 na 0,3 mg / dl. 

Rịba ama na ihe a na-akpọ ụkpụrụ nkịtị nke bilirubin n'ime ọbara nwere ike ịdị iche dabere na ụlọ nyocha na-eme nyocha.

Naanị dọkịta nwere ike ịkọwa nsonaazụ ya wee nye gị nyocha.

Ọ bụrụ na ọkwa bilirubin dị elu, a na-akpọ yahyperbilirubinémie.

Ọ nwere ike ịbụ:

• oke nke ụdị efu (site na mmepụta oke ma ọ bụ enweghị njikọ):

- mmịnye ọbara nke mberede

- hemolytic anaemia: egbu egbu, ọgwụ, parasitic hemolysis, wdg.

- ọrịa Gilbert (mkpụrụ ndụ ihe nketa nke bilirubin metabolism).

- jaundice nke nwa amụrụ ọhụrụ

Criggler-Najjar syndrome (nsogbu ketara eketa nke bilirubin metabolism)

• ọkaibe nke ụdị conjugated (a na-ahapụ bilirubin conjugated na mgbasa mgbe a na-egbochi ụzọ nke excretion nkịtị):

- nkume gallstone

neoplasia (ọrịa cancer)

- pancreatitis

- ịba ọcha n'anya, ịba ọcha n'anya, ịba ọcha n'anya

- cirrhosis

Otu n'ime ihe dị iche iche bụ "jaundice na free bilirubin", nke bụ kama n'ihi oke mbibi nke mkpụrụ ndụ ọbara uhie (hemolysis) nke "jaundice nwere conjugated bilirubin", kama metụtara ọrịa biliary ma ọ bụ imeju.