Febụwarị 24, 2012-Ọ bụ ezie na a na-ejikarị ya eme ihe, ọgwụ mgbochi mkpali na-abụghị steroid (NSAID) yiri ka ọ na-ebute ezigbo ahụike. N'ime ndị a kacha mara bụ aspirin, Advil®, Antadys®, Ibuprofen® ma ọ bụ ọbụna Voltarene®, ọgwụ ndị a na -edekarị.

Klas a nke ọgwụ mgbochi mkpali na-eche na ọ nwere ike imebi obi na akụrụ. N'ezie, ndị NSAID ejirila maka:

• obi ọrịa

Iji mee ka ihe mgbu ahụ dajụọ, ọgwụ mgbochi mkpali na-abụghị steroid na-egbochi ọrụ nke enzymes abụọ (= protein na-enye ohere ime ihe ndị dị ndụ) akpọrọ COX-1 na COX-2.

Igbochi COX-2 nke ndị NSAID na-egbochi ikpukọ ọbara na njikọ nke thromboxanes, homonụ nwere ọrụ vasoconstrictor, si otu a na-abawanye ọbara mgbali na ihe egwu nke obi.

• Ọnya ọnya na ọbara ọgbụgba na tract digestive

COX-1 na-enye ohere iguzobe prostaglandins, metabolites nke emepụtara na splin, akụrụ na obi. Mgbochi nke COX-1 site na ọgwụ mgbochi mkpali na-abụghị steroid na-egbochi ya ichebe akụkụ nri, wee si otu a bute ọnya afọ.

• Ọkpụkpụ akụrụ

Mgbochi a nke COX-1 ga-akwalitekwa ọdịda akụrụ site na ịmachi nsị nke akụrụ.

Na mkpokọta, ọ bụ ndị agadi na-enwekarị ihe egwu ndị a, n'ihi na ọrụ akụrụ ha na-ebelata, ihe mgbagwoju anya, mgbe anyị maara na a na-enye ọgwụ mgbochi mkpali iji belata mgbu metụtara osteoarthritis.

Anaïs Lhôte - PasseportSanté.net

Isi Iyi: Ọgwụ gị, Philippe onye nkuzi