The D-dimer sitere na mmebi nke fibrin, protein na-etinye aka na mkpụkọ ọbara.

Mgbe ọbara na-akpụ akpụ, dịka ọmụmaatụ na mmerụ ahụ, ụfọdụ ndị mejupụtara ya na-ejikọta onwe ha na ibe ha, karịsịa site n'enyemaka nke fibrin.

Mgbe enweghi mkpụkọ ọbara zuru oke, ọ nwere ike ịkpata ọbara ọgbụgba na mberede (ọbara ọgbụgba). N'ụzọ megidere nke ahụ, mgbe ọ bụ oke, ọ nwere ike jikọta ya na nhazi nke nkedo ọbara nke nwere ike ịkpata mmerụ ahụ (thrombosis miri emi, pulmonary embolism). N'okwu a, a na-etinye usoro nchebe iji mebie fibrin na-abaghị uru ma belata ya na iberibe, ụfọdụ n'ime ha bụ D-dimers. Ya mere ọnụnọ ha nwere ike ịgba akaebe na e guzobere mkpụkọ ọbara.

Dọkịta ga-edepụta ule D-dimer ma ọ bụrụ na ọ na-enyo enyo na ọnụnọ nke mkpịsị ọbara. Ndị a nwere ike ịkpata nnukwu nsogbu, dịka:

• a miri akwara thrombosis (a na-akpọkwa ya phlebitis miri emi, ọ na-esite na nguzobe nke clot na netwọk venous nke akụkụ ụkwụ ala)

• pulmonary embolism (ọnụnọ nke clot na-enweghị akwara akpa ume)

• ma ọ bụ a ọrịa strok

A na-eme usoro onunu D-dimers site na nlele ọbara venous, a na-eme ya n'ogo nke mpịachi nke ikpere. A na-achọpụtakarị ha site na ụzọ mgbochi ọrịa (iji ọgwụ mgbochi ọrịa).

Ọ dịghị nkwadebe pụrụ iche achọrọ.

Ọnụnọ nke D-dimer n'ọbara na-adịkarị obere karịa 500 μg / l (microgram kwa liter).

Ihe nyocha D-dimer nwere oke amụma amụma adịghị mma. N'ikwu ya n'ụzọ ọzọ, nsonaazụ nkịtị na-enye ohere iwepụ nchọpụta nke thrombosis miri emi na pulmonary embolism. N'aka nke ọzọ, ọ bụrụ na achọpụtara ọkwa D-dimer dị elu, a na-enyo enyo na ọnụnọ nke clot na-egosi na ọ ga-ekwe omume thrombosis miri emi ma ọ bụ pulmonary embolism. A ga-enyocharịrị nsonaazụ a site na nyocha ndị ọzọ (karịsịa site na onyonyo): Ya mere a ga-eji nlezianya kọwaa nyocha ahụ.

Enwere n'ezie okwu nke mmụba nke ọkwa D-dimers na-enweghị njikọ na ọnụnọ nke thrombosis miri emi na pulmonary embolism. Ka anyị kwuo okwu:

• afọ ime

• ọrịa imeju

• mfu ọbara

• resorption nke hematoma,
• ịwa ahụ na nso nso a

• ọrịa ogbu na nkwonkwo (dị ka rheumatoid ogbu na nkwonkwo)

• ma ọ bụ naanị ime agadi (karịa 80)

Rịba ama na mkpebi nke D-dimers bụ usoro na-adịbeghị anya (ebe ọ bụ na njedebe nke 90s), na ụkpụrụ ka bụ isiokwu nke ajụjụ. N'ihi na na France, a na-eguzobe ọkwa dị ka ihe na-erughị 500 µg / l, ebe na United States, a na-ebelata ọnụ ụzọ a na 250 µg / l.